In June, the National Institutes of Health (NIH) All of Us Research Program unveiled the world’s most extensive health database. More than 747,000 Americans from all 50 states contributed data, encompassing 535,000 complete genomes associated with 482,000 electronic health records and data from wearable technology like Fitbit. The database also includes participants’ socioeconomic information, sleep data and location-based air quality statistics. The database’s most significant advantage lies in its diverse participant pool. By contrast, the other leading health database, UK Biobank, includes genetic and other information on 500,000 participants, predominantly of white European descent.

The NIH program began enrolling participants in 2018 with a goal of including 1 million Americans for at least 10 years to study the interplay between genes and lifestyle and environmental factors. More than 23,000 researchers have used the database and authored more than 1,400 peer-reviewed publications. Despite the NIH announcement, the program’s funding is scheduled to expire at the end of 2026. More than 50 medical organizations have petitioned Congress to allocate new funding or risk losing what has been built.